Single dose tetracycline in cholera.
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منابع مشابه
Single dose tetracycline in cholera
A randomised clinical trial was carried out to explore the efficacy of single dose tetracycline therapy in cholera. One hundred and eighteen adult patients were assigned to receive either tetracycline in a single 1 g, or a single 2 g dose, or tetracycline 500 mg every six hours four times, or no antibiotics as controls. The means of total liquid stool volumes after treatment were lower in the s...
متن کاملTetracycline resistant cholera in Kelantan.
Sensitivity testing on Vibrio cholerae isolates during an epidemic in 1998 in Kelantan identified strains resistant to tetracycline. This prompted a change in the usual management of cholera in Kelantan. The antibiotic of choice was changed from tetracycline to erythromycin.
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BACKGROUND Single-dose azithromycin is effective in the treatment of severe cholera in children, but its effectiveness in adults has not been evaluated. METHODS We conducted a double-blind, randomized trial comparing the equivalence of azithromycin and ciprofloxacin (each given in a single 1-g dose of two 500-mg tablets) among 195 men with severe cholera caused by Vibrio cholerae O1 or O139. ...
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Six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. Blood samples were collected before and at various time intervals after the administration of the drug. Serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. Non...
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OBJECTIVE To compare the clinical and bacteriological success of single dose treatment with azithromycin and ciprofloxacin in children with cholera. DESIGN Randomized, open labelled, clinical controlled trial. SETTING Tertiary care hospital. PARTICIPANTS 180 children between 2-12 years, having watery diarrhea for < or = 24 hr and severe dehydration, who tested positive for Vibrio cholerae...
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ژورنال
عنوان ژورنال: Gut
سال: 1987
ISSN: 0017-5749
DOI: 10.1136/gut.28.8.1029